CARD 11 rabbit pAb

CARD 11 rabbit pAb

Item number: ES1840
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CARD 11 rabbit pAb

CARD 11 rabbit pAb

$148.00

CARD 11 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CARD11. AA range:10-59
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
130kD
Geneid human
84433
Human swiss prot no
Q9BXL7
Cellular localization
Cytoplasm . Membrane raft . Colocalized with DPP4 in membrane rafts. .
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],

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