CARD11 (phospho-Ser652) rabbit pAb

Item number: ES17855
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CARD11 (phospho-Ser652) rabbit pAb

$148.00

CARD11 (phospho-Ser652) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:1000-2000
Immunogen
Synthesized phosho peptide around human CARD11 (Ser652)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
130kD
Geneid human
84433
Human swiss prot no
Q9BXL7
Cellular localization
Cytoplasm . Membrane raft . Colocalized with DPP4 in membrane rafts. .
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],

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