Product Overview
Product Overview
Applications
WB;IHC;IP;IF;ELISA
Cellular localization
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
1434
Human swiss prot no
P55060
Immunogen
The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50
Isotype
IgG
Observed band
110kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Product Citations
Product Citations
More Info
More Info
CAS rabbit pAb
CAS rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1844
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;IHC;IP;IF;ELISA
Cellular localization
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
1434
Human swiss prot no
P55060
Immunogen
The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50
Isotype
IgG
Observed band
110kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Product Citations
Product Citations
More Info
More Info
CAS rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
