Caspase 10 (p12, Cleaved-Ala416) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES19952

$148.00

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Documents

Manual

Available in stock (100)

Size: 50μL

50μL 100μL

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Product Overview

Applications

WB; ELISA

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

74

Geneid human

843

Human swiss prot no

Q92851

Immunogen

Synthesized peptide derived from human Caspase 10 (p12, Cleaved-Ala416)

Isotype

IgG

Observed band

12 55kD

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

WB 1:1000-2000 ELISA 1:5000-20000

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Background

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],

Caspase 10 (p12, Cleaved-Ala416) rabbit pAb