Caspase-10 rabbit pAb

Caspase-10 rabbit pAb

Item number: ES3824
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Caspase-10 rabbit pAb

Caspase-10 rabbit pAb

$148.00

Caspase-10 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from the Internal region of human Caspase-10.
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
58kD
Geneid human
843
Human swiss prot no
Q92851
Cellular localization
cytosol,CD95 death-inducing signaling complex,ripoptosome,
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],

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