Caspase 2 (p13, Cleaved-Gly334) rabbit pAb

Item number: ES19955
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Caspase 2 (p13, Cleaved-Gly334) rabbit pAb

$148.00

Caspase 2 (p13, Cleaved-Gly334) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB; ELISA
Source
Rabbit
Recommended dilutions
WB 1:1000-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human Caspase 2 (p13, Cleaved-Gly334)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
13 50kD
Geneid human
835
Human swiss prot no
P42575
alternative products:Isoforms differ in the N- and C-termini,catalytic activity:Strict requirement for an Asp residue at P1, with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,PTM:The mature protease can process its own propeptide, but not that of other caspases.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.,tissue specificity:Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.,

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