Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
nucleus,mitochondrion,cytosol,apoptosome,
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
842
Human swiss prot no
P55211
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 9 around the phosphorylation site of Ser144. AA range:110-159
Isotype
IgG
Observed band
35kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Product Citations
Product Citations
More Info
More Info
Caspase-9 (phospho Ser144) rabbit pAb
Caspase-9 (phospho Ser144) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES7742
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
nucleus,mitochondrion,cytosol,apoptosome,
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
842
Human swiss prot no
P55211
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 9 around the phosphorylation site of Ser144. AA range:110-159
Isotype
IgG
Observed band
35kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Product Citations
Product Citations
More Info
More Info
Caspase-9 (phospho Ser144) rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
