Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
endoplasmic reticulum,IPAF inflammasome complex,NLRP3 inflammasome complex,AIM2 inflammasome complex,
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
120329
Human swiss prot no
Q6UXS9
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase12. AA range:50-99
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011],
Product Citations
Product Citations
More Info
More Info
Caspase12 rabbit pAb
Caspase12 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1852
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
endoplasmic reticulum,IPAF inflammasome complex,NLRP3 inflammasome complex,AIM2 inflammasome complex,
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
120329
Human swiss prot no
Q6UXS9
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase12. AA range:50-99
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011],
Product Citations
Product Citations
More Info
More Info
Caspase12 rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
