CASQ1 rabbit pAb

CASQ1 rabbit pAb

Item number: ES17843
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CASQ1 rabbit pAb

CASQ1 rabbit pAb

$148.00

CASQ1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Applications
WB
Source
Rabbit
Recommended dilutions
WB 1:500-2000
Immunogen
Synthesized peptide derived from human CASQ1 AA range: 322-372
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
844
Human swiss prot no
P31415
Cellular localization
Endoplasmic reticulum . Sarcoplasmic reticulum . Sarcoplasmic reticulum lumen . Sarcoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side . Mitochondrion matrix . This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Preferentially forms linear and round aggregates in the endoplasmic reticulum (ER) of resting cells (PubMed:28895244). In a minority of cells, homogeneously detected in the ER lumen (PubMed:28895244). Colocalizes with STIM1 at endoplasmic reticulum in response to a depletion of intracellular calcium (PubMed:27185316). .
This gene encodes the skeletal muscle specific member of the calsequestrin protein family. Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells. This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle. This protein is absent in patients with Duchenne and Becker types of muscular dystrophy. [provided by RefSeq, Jun 2013],

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