CaSR (phospho Thr888) rabbit pAb

CaSR (phospho Thr888) rabbit pAb

Item number: ES7763
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CaSR (phospho Thr888) rabbit pAb

CaSR (phospho Thr888) rabbit pAb

$148.00

CaSR (phospho Thr888) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor around the phosphorylation site of Thr888. AA range:854-903
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
140kD
Geneid human
846
Human swiss prot no
P41180
Cellular localization
Cell membrane ; Multi-pass membrane protein .
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008],

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