Catalase rabbit pAb

Catalase rabbit pAb

Item number: ES3885
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Catalase rabbit pAb

Catalase rabbit pAb

$148.00

Catalase rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;;Fish
Applications
IF;WB;IHC;ELISA
Source
Rabbit
Recommended dilutions
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human CAT. AA range:478-527
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
60kD
Geneid human
847
Human swiss prot no
P04040
Cellular localization
Peroxisome.
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009],

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