CATL1 (heavy chain, Cleaved-Ala114) rabbit pAb

Item number: ES19961
Availability: In Stock
$148.00
$148.00
Please hurry! Only 100 left in stock

Documents

Size: 50μL
Subtotal: $148.00
×

Request a Quote

Thank you! We’ll contact you soon.

10 customers are viewing this product

Customized & fast shipping

Terms and Conditions

Vareum

CATL1 (heavy chain, Cleaved-Ala114) rabbit pAb

$148.00

CATL1 (heavy chain, Cleaved-Ala114) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB; ELISA
Source
Rabbit
Recommended dilutions
WB 1:1000-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human CATL1 (heavy chain, Cleaved-Ala114)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
25 37kD
Geneid human
1514
Human swiss prot no
P07711
Cellular localization
Lysosome . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Cytoplasmic vesicle, secretory vesicle, chromaffin granule . Secreted, extracellular space . Secreted . Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages. .; [Isoform 2]: Nucleus . Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and do not transit through the endoplasmic reticulum to localize to the nucleus (PubMed:15099520). Nuclear location varies during the cell cycle, with higher levels during S phase (PubMed:15099520). .
catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,

Related Products

Recently Viewed Products