Product Overview
Product Overview
Applications
IHC;IF
Cellular localization
Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Perikaryon . Cell junction, synapse, postsynaptic density membrane . Cell projection, dendrite . Cell membrane, sarcolemma, T-tubule . Colocalizes with ryanodine receptors in distinct clusters at the junctional membrane, where the sarcolemma and the sarcoplasmic reticulum are in close contact. The interaction between RRAD and CACNB2 promotes the expression of CACNA1C at the cell membrane. .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
775
Human swiss prot no
Q13936
Immunogen
Synthetic Peptide of Cav1.2
Isotype
IgG
Observed band
160-240kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
IHC 1:100-200
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
calcium voltage-gated channel subunit alpha1 C(CACNA1C) Homo sapiens This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012],
Product Citations
Product Citations
More Info
More Info
Cav1.2 Rabbit pAb
Cav1.2 Rabbit pAb
Vendor: ELK Biotechnology
SKU: ES20798
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
IHC;IF
Cellular localization
Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Perikaryon . Cell junction, synapse, postsynaptic density membrane . Cell projection, dendrite . Cell membrane, sarcolemma, T-tubule . Colocalizes with ryanodine receptors in distinct clusters at the junctional membrane, where the sarcolemma and the sarcoplasmic reticulum are in close contact. The interaction between RRAD and CACNB2 promotes the expression of CACNA1C at the cell membrane. .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
775
Human swiss prot no
Q13936
Immunogen
Synthetic Peptide of Cav1.2
Isotype
IgG
Observed band
160-240kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
IHC 1:100-200
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Background
Background
calcium voltage-gated channel subunit alpha1 C(CACNA1C) Homo sapiens This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012],
Product Citations
Product Citations
More Info
More Info
Cav1.2 Rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
