CBX2 rabbit pAb

CBX2 rabbit pAb

Item number: ES7779
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CBX2 rabbit pAb

CBX2 rabbit pAb

$148.00

CBX2 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from the N-terminal region of human CBX2.
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
84733
Human swiss prot no
Q14781
Cellular localization
Nucleus . Chromosome . Localized in distinct foci on chromatin and in chromocenters. Localizes to the inactive X chromosome. Seems to be recruited to H3K27me3, H3K9ac and H3K3me2 sites on chromatin. .
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010],

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