CCR10 rabbit pAb

CCR10 rabbit pAb

Item number: ES11457
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CCR10 rabbit pAb

CCR10 rabbit pAb

$148.00

CCR10 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
39kD
Geneid human
2826
Human swiss prot no
P46092
Cellular localization
Cell membrane; Multi-pass membrane protein.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900])

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