CCR8 rabbit pAb

CCR8 rabbit pAb

Item number: ES11458
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CCR8 rabbit pAb

CCR8 rabbit pAb

$148.00

CCR8 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 250-330
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
39kD
Geneid human
1237
Human swiss prot no
P51685
Cellular localization
Cell membrane; Multi-pass membrane protein.
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008],

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