CCRL1 rabbit pAb
CCRL1 rabbit pAb

CCRL1 rabbit pAb

Item number: ES1891
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CCRL1 rabbit pAb

CCRL1 rabbit pAb

$148.00

CCRL1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CCRL1. AA range:291-340
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
40kD
Geneid human
51554
Human swiss prot no
Q9NPB9
Cellular localization
Early endosome . Recycling endosome . Cell membrane ; Multi-pass membrane protein . Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013],

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