CD13 rabbit pAb

CD13 rabbit pAb

Item number: ES4309
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD13 rabbit pAb

CD13 rabbit pAb

$148.00

CD13 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
Synthesized peptide derived from Aminopeptidase N at AA range: 881-930
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
110kD
Geneid human
290
Human swiss prot no
P15144
Cellular localization
Cell membrane ; Single-pass type II membrane protein . Also found as a soluble form. .
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is

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