CD130/gp130 (Phospho-Ser782) rabbit pAb

CD130/gp130 (Phospho-Ser782) rabbit pAb

Item number: ES17738
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD130/gp130 (Phospho-Ser782) rabbit pAb

CD130/gp130 (Phospho-Ser782) rabbit pAb

$148.00

CD130/gp130 (Phospho-Ser782) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse
Applications
IHC;IF;WB
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Immunogen
Synthesized peptide derived from human CD130/gp130 (Phospho-Ser782)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
130kD
Geneid human
3572
Human swiss prot no
P40189
Cellular localization
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014],

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