CD16 rabbit pAb

CD16 rabbit pAb

Item number: ES8675
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD16 rabbit pAb

CD16 rabbit pAb

$148.00

CD16 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 100-150
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2214
Human swiss prot no
P08637/O75015
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Secreted . Exists also as a soluble receptor. .
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,

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