CD192 rabbit pAb

CD192 rabbit pAb

Item number: ES4365
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD192 rabbit pAb

CD192 rabbit pAb

$148.00

CD192 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR2. AA range:1-50
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
42kD
Geneid human
729230
Human swiss prot no
P41597
Cellular localization
Cell membrane ; Multi-pass membrane protein . The chemoattractant receptors are distributed throughout the cell surface; after stimulation with a ligand, such as CCL2, they are rapidly recruited into microdomain clusters at the cell membrane. .
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009],

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