CD1A/B rabbit pAb

CD1A/B rabbit pAb

Item number: ES8784
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD1A/B rabbit pAb

CD1A/B rabbit pAb

$148.00

CD1A/B rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 220-270
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
909/910
Human swiss prot no
P06126/P29016
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838). .
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

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