CD1B rabbit pAb

CD1B rabbit pAb

Item number: ES8672
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD1B rabbit pAb

CD1B rabbit pAb

$148.00

CD1B rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 60-100
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
910
Human swiss prot no
P29016
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. .
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008],

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