Product Overview
Product Overview
Applications
IHC;IF;ELISA
Cellular localization
Membrane; Single-pass type II membrane protein.
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
4481
Human swiss prot no
P21757
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MSR1. AA range:241-290
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type
Product Citations
Product Citations
More Info
More Info
CD204 rabbit pAb
CD204 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8700
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
IHC;IF;ELISA
Cellular localization
Membrane; Single-pass type II membrane protein.
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
4481
Human swiss prot no
P21757
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MSR1. AA range:241-290
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type
Product Citations
Product Citations
More Info
More Info
CD204 rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
