CD21 Mouse mAb

CD21 Mouse mAb

Item number: EM1060
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD21 Mouse mAb

CD21 Mouse mAb

$148.00

CD21 Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Applications
IHC
Source
Mouse
Recommended dilutions
IHC 1:200
Immunogen
Synthetic Peptide
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Observed band
113kDa
Geneid human
1380
Human swiss prot no
P20023
Cellular localization
Membrane
CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.

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