CD275 rabbit pAb

CD275 rabbit pAb

Item number: ES8796
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD275 rabbit pAb

CD275 rabbit pAb

$148.00

CD275 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 201-250
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
23308
Human swiss prot no
O75144
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
alternative products:Additional isoforms seem to exist,function:Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.,induction:Constitutive expression is further enhanced by treatment with TNF-alpha in peripheral blood B-cells and monocytes, while it is decreased in dendritic cells.,sequence caution:The sequence differs from that shown in position 300 onward for unknown reason.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.,

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