CD30-L rabbit pAb

CD30-L rabbit pAb

Item number: ES5686
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD30-L rabbit pAb

CD30-L rabbit pAb

$148.00

CD30-L rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD153. AA range:71-120
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
38kD
Geneid human
2965
Human swiss prot no
P32971
Cellular localization
Membrane; Single-pass type II membrane protein.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

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