CD35 rabbit pAb

CD35 rabbit pAb

Item number: ES8467
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD35 rabbit pAb

CD35 rabbit pAb

$148.00

CD35 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000, ELISA 1:10000-20000
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CR1/CR1L. AA range:300-350 & 740-790
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
220kD
Geneid human
1378
Human swiss prot no
P17927/Q2VPA4
Cellular localization
Membrane ; Single-pass type I membrane protein.
This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants

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