CD4 Mouse mAb

CD4 Mouse mAb

Item number: EM1070
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD4 Mouse mAb

CD4 Mouse mAb

$148.00

CD4 Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Applications
IHC
Source
Mouse
Recommended dilutions
IHC 1:100-200
Immunogen
Synthetic Peptide
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Geneid human
920
Human swiss prot no
P01730
Cellular localization
Cell membrane
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 geneGalectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.

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