CD42c rabbit pAb

CD42c rabbit pAb

Item number: ES8786
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD42c rabbit pAb

CD42c rabbit pAb

$148.00

CD42c rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 90-150
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2812
Human swiss prot no
P13224
Cellular localization
Membrane; Single-pass type I membrane protein.
Platelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, t

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