CD45 Mouse mAb

CD45 Mouse mAb

Item number: EM1046
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD45 Mouse mAb

CD45 Mouse mAb

$148.00

CD45 Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human
Applications
WB
Source
Mouse
Recommended dilutions
WB 1:2,000 IHC 1:200
Immunogen
Synthetic Peptide
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Observed band
147kDa
Geneid human
5788
Human swiss prot no
P08575
Cellular localization
Membrane
CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.

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