CD5 Mouse mAb

CD5 Mouse mAb

Item number: EM1071
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD5 Mouse mAb

CD5 Mouse mAb

$148.00

CD5 Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Applications
IHC
Source
Mouse
Recommended dilutions
IHC 1:100-200
Immunogen
Synthetic Peptide
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Geneid human
921
Human swiss prot no
P06127
Cellular localization
Membrane
CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.

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