CD53 rabbit pAb

CD53 rabbit pAb

Item number: ES4321
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD53 rabbit pAb

CD53 rabbit pAb

$148.00

CD53 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
24kD
Geneid human
963
Human swiss prot no
P19397
Cellular localization
Cell membrane . Cell junction . Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. .
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

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