CD6 rabbit pAb
CD6 rabbit pAb

CD6 rabbit pAb

Item number: ES7995
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD6 rabbit pAb

CD6 rabbit pAb

$148.00

CD6 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD6. AA range:250-299
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
73kD
Geneid human
923
Human swiss prot no
P30203
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with the TCR/CD3 complex at the immunological synapse (PubMed:15294938). .; [Soluble CD6]: Secreted . The origins of the secreted form are not clear, but it might be created by proteolytic shedding of the ectodomain. .
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

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