CD68 Mouse mAb
CD68 Mouse mAb

CD68 Mouse mAb

Item number: EM1162
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD68 Mouse mAb

CD68 Mouse mAb

$148.00

CD68 Mouse mAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Applications
IHC
Source
Mouse
Recommended dilutions
IHC 1:200-500
Immunogen
Synthetic Peptide
Isotype
IgG1
Clonality
Monoclonal
Concentration
1mg/mL
Geneid human
968
Human swiss prot no
P34810
Cellular localization
Cell membrane and Endosome membrane. Lysosome membrane
The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.

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