Product Overview
Product Overview
Applications
IHC
Cellular localization
Cell membrane and Endosome membrane. Lysosome membrane
Clonality
Monoclonal
Concentration
1mg/mL
Cost per item
74
Geneid human
968
Human swiss prot no
P34810
Immunogen
Synthetic Peptide
Isotype
IgG1
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Recommended dilutions
IHC 1:200-500
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Documents
Documents
Documents
Backgrond
Backgrond
The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Product Citations
Product Citations
More Info
More Info
CD68 Mouse mAb
CD68 Mouse mAb
Vendor: ELK Biotechnology
SKU: EM1162
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
IHC
Cellular localization
Cell membrane and Endosome membrane. Lysosome membrane
Clonality
Monoclonal
Concentration
1mg/mL
Cost per item
74
Geneid human
968
Human swiss prot no
P34810
Immunogen
Synthetic Peptide
Isotype
IgG1
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Recommended dilutions
IHC 1:200-500
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Documents
Documents
Documents
Backgrond
Backgrond
The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
Product Citations
Product Citations
More Info
More Info
CD68 Mouse mAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per

