CD68 rabbit pAb

CD68 rabbit pAb

Item number: ES3940
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD68 rabbit pAb

CD68 rabbit pAb

$148.00

CD68 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD68. AA range:171-220
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
37kD
Geneid human
968
Human swiss prot no
P34810
Cellular localization
[Isoform Short]: Cell membrane; Single-pass type I membrane protein.; [Isoform Long]: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],

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