CD8A rabbit pAb

Item number: ES20412
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD8A rabbit pAb

$148.00

CD8A rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB; ELISA
Source
Rabbit
Recommended dilutions
WB 1:1000-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human CD8A
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
925
Human swiss prot no
P01732
Cellular localization
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein. CD8A localizes to lipid rafts only when associated with its partner CD8B. .; [Isoform 2]: Secreted .
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

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