Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Membrane raft .; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
355
Human swiss prot no
P25445
Immunogen
The antiserum was produced against synthesized peptide derived from human FAS. AA range:281-330
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, s
Product Citations
Product Citations
More Info
More Info
CD95 rabbit pAb
CD95 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1920
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
×
Request a Quote
- Free Shipping over $2500
- AI AgentFor Any Questions or Product Search Help
- Track Your Order Status Anytime
Couldn't load pickup availability
Limited time offer
Get $200 off when you spend $2,500 or more!
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Membrane raft .; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
355
Human swiss prot no
P25445
Immunogen
The antiserum was produced against synthesized peptide derived from human FAS. AA range:281-330
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, s
Product Citations
Product Citations
More Info
More Info
CD95 rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
