Cdc27 rabbit pAb

Cdc27 rabbit pAb

Item number: ES1928
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Cdc27 rabbit pAb

Cdc27 rabbit pAb

$148.00

Cdc27 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human H-NUC. AA range:361-410
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
92kD
Geneid human
996
Human swiss prot no
P30260
Cellular localization
Nucleus . Cytoplasm, cytoskeleton, spindle .
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been i

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