Cdc6 (phospho Ser54) rabbit pAb

Cdc6 (phospho Ser54) rabbit pAb

Item number: ES8123
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Cdc6 (phospho Ser54) rabbit pAb

Cdc6 (phospho Ser54) rabbit pAb

$148.00

Cdc6 (phospho Ser54) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Monkey
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CDC6 around the phosphorylation site of Ser54. AA range:20-69
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
62kD
Geneid human
990
Human swiss prot no
Q99741
Cellular localization
Nucleus . Cytoplasm . The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895). .
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008],

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