CENP-M rabbit pAb

CENP-M rabbit pAb

Item number: ES17525
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CENP-M rabbit pAb

CENP-M rabbit pAb

$148.00

CENP-M rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
IHC;IF;WB
Source
Rabbit
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Immunogen
Synthesized peptide derived from human CENP-M AA range: 30-110
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
20kD
Geneid human
79019
Human swiss prot no
Q9NSP4
Cellular localization
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of centromeres. .
The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

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