Product Overview
Product Overview
Applications
IHC;IF;WB
Cellular localization
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of centromeres. .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
79019
Human swiss prot no
Q9NSP4
Immunogen
Synthesized peptide derived from human CENP-M AA range: 30-110
Isotype
IgG
Observed band
20kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Product Citations
Product Citations
More Info
More Info
CENP-M rabbit pAb
CENP-M rabbit pAb
Vendor: ELK Biotechnology
SKU: ES17525
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
IHC;IF;WB
Cellular localization
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of centromeres. .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
79019
Human swiss prot no
Q9NSP4
Immunogen
Synthesized peptide derived from human CENP-M AA range: 30-110
Isotype
IgG
Observed band
20kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Product Citations
Product Citations
More Info
More Info
CENP-M rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
