Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
9702
Human swiss prot no
Q86XR8
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP57. AA range:241-290
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple
Product Citations
Product Citations
More Info
More Info
CEP57 rabbit pAb
CEP57 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8087
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Clonality
Polyclonal
Concentration
1 mg/ml
Cost per item
74
Geneid human
9702
Human swiss prot no
Q86XR8
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP57. AA range:241-290
Isotype
IgG
Observed band
50kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Documents
Documents
Documents
Backgrond
Backgrond
This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple
Product Citations
Product Citations
More Info
More Info
CEP57 rabbit pAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
