Product Overview

Applications

IF;ELISA

Cellular localization

Early endosome. Recycling endosome. Cell membrane; Multi-pass membrane protein. Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via clathrin-coated pits. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

Geneid human

1238

Human swiss prot no

O00590

Immunogen

The antiserum was produced against synthesized peptide derived from human CCBP2. AA range:335-384

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Backgrond

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008],

Product Citations

More Info

Chemokine Receptor D6 rabbit pAb

Vendor: ELK Biotechnology

SKU: ES4713

$148.00

Shipping calculated at checkout.

Documents

Manual

Available in stock (100)

Size: 50μL

50μL 100μL

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Product Overview

Applications

IF;ELISA

Cellular localization

Clonality

Polyclonal

Concentration

1 mg/ml

Cost per item

Geneid human

1238

Human swiss prot no

O00590

Immunogen

The antiserum was produced against synthesized peptide derived from human CCBP2. AA range:335-384

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Documents

Manual

Backgrond

Product Citations

More Info