Product Overview
Product Overview
Applications
IHC
Cellular localization
Intermediate filament
Clonality
Monoclonal
Concentration
1mg/mL
Cost per item
74
Geneid human
3868
Human swiss prot no
P08779
Immunogen
Synthetic Peptide
Isotype
IgG1
Observed band
51kDa
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Recommended dilutions
IHC 1:200
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Documents
Documents
Documents
Backgrond
Backgrond
Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Product Citations
Product Citations
More Info
More Info
CK16 Mouse mAb
CK16 Mouse mAb
Vendor: ELK Biotechnology
SKU: EM1056
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
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Product Overview
Product Overview
Applications
IHC
Cellular localization
Intermediate filament
Clonality
Monoclonal
Concentration
1mg/mL
Cost per item
74
Geneid human
3868
Human swiss prot no
P08779
Immunogen
Synthetic Peptide
Isotype
IgG1
Observed band
51kDa
Product weight
0.005kg
Reactivity
Human, Rat, Mouse
Recommended dilutions
IHC 1:200
Source
Mouse
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Documents
Documents
Documents
Backgrond
Backgrond
Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Product Citations
Product Citations
More Info
More Info
CK16 Mouse mAb
Regular price
$148.00
Sale price
$148.00
Regular price
Unit price
/per

