Lapaquistat acetate

Vendor: Abmole

Type: Molecular

SKU: M28996

$402.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway. Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research.
Casnumber
189060-13-7
Formula
C33H41ClN2O9
Mw
645.14
Psmiles
CC(=O)OCC(C)(C)CN1C2=C(C=C(C=C2)Cl)C(OC(C1=O)CC(=O)N3CCC(CC3)CC(=O)O)C4=C(C(=CC=C4)OC)OC
Purity
≥99.0%
Solubility
DMSO 50 mg/mL (ultrasonic)
Target synonyms
TAK-475
Lapaquistat acetate

Lapaquistat acetate

$402.50 USD