MYP0 rabbit pAb

MYP0 rabbit pAb

Item number: ES9836
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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MYP0 rabbit pAb

MYP0 rabbit pAb

$148.00

MYP0 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
27kD
Geneid human
4359
Human swiss prot no
P25189
Cellular localization
Cell membrane ; Single-pass type I membrane protein.; [Isoform L-MPZ]: Myelin membrane ; Single-pass type I membrane protein .
This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2015],

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