NIPBL rabbit pAb

NIPBL rabbit pAb

Item number: ES9928
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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NIPBL rabbit pAb

NIPBL rabbit pAb

$148.00

NIPBL rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
IHC;IF
Source
Rabbit
Recommended dilutions
IHC-p 1:50-300
Immunogen
Synthesized peptide derived from human protein . at AA range: 560-640
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
308kD
Geneid human
25836
Human swiss prot no
Q6KC79
Cellular localization
Nucleus . Chromosome .
This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

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