PCM1 rabbit pAb

Item number: ES9976
Availability: In Stock
$148.00
$148.00
Please hurry! Only 100 left in stock

Documents

Size: 50μL
Subtotal: $148.00
10 customers are viewing this product

Customized & fast shipping

Terms and Conditions

Vareum

PCM1 rabbit pAb

$148.00

PCM1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
222kD
Geneid human
5108
Human swiss prot no
Q15154
Cellular localization
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasmic granule . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cytoplasm, cytoskeleton, cilium basal body . Recruitment to the centrosome requires microtubules and dynein. The majority of the protein dissociates from the centrosome during metaphase and subsequently localizes to the cleavage site in telophase. Displaced from centriolar satellites and centrosome in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock, in a process that requires p38 MAP kinase signaling.
pericentriolar material 1(PCM1) Homo sapiens The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

Related Products

Recently Viewed Products