Product Overview
Product Overview
Abbreviation
Recombinant Sheep FGF2 protein (Active)
Alternative names
Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor (bFGF); Heparin-binding growth factor 2 (HBGF-2); FGF2
Buffer [rich text]
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Expression region
10-155aa
Form
Lyophilized powder
Gene names
FGF2
Mw
17.9 kDa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Organism
Ovis aries (Sheep)
Protein length
Full Length of Mature Protein
Purity
Greater than 95% as determined by SDS-PAGE.
Reconstitution [rich text]
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Reference [rich text]
/
Relevance
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4.
Also acts as an integrin ligand which is required for FGF2 signaling.
Binds to integrin ITGAV:ITGB3.
Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration.
Functions as a potent mitogen in vitro.
Can induce angiogenesis.
Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation.
Research area
Cancer
Sds description [rich text]
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Source
Yeast
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Tag info
C-terminal 6xHis-tagged
Target protein sequenc
PALPEDGGSSAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKS
Uniprot id
P20003
Documents
Documents
Background
Background
Product Citations
Product Citations
More Info
More Info
Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active)
Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active)
Regular price
$2,310.00
Sale price
$2,310.00
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (500)
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Product Overview
Product Overview
Abbreviation
Recombinant Sheep FGF2 protein (Active)
Alternative names
Fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor (bFGF); Heparin-binding growth factor 2 (HBGF-2); FGF2
Buffer [rich text]
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Expression region
10-155aa
Form
Lyophilized powder
Gene names
FGF2
Mw
17.9 kDa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Organism
Ovis aries (Sheep)
Protein length
Full Length of Mature Protein
Purity
Greater than 95% as determined by SDS-PAGE.
Reconstitution [rich text]
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Reference [rich text]
/
Relevance
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4.
Also acts as an integrin ligand which is required for FGF2 signaling.
Binds to integrin ITGAV:ITGB3.
Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration.
Functions as a potent mitogen in vitro.
Can induce angiogenesis.
Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation.
Research area
Cancer
Sds description [rich text]
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Source
Yeast
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Tag info
C-terminal 6xHis-tagged
Target protein sequenc
PALPEDGGSSAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKS
Uniprot id
P20003
Documents
Documents
Background
Background
Product Citations
Product Citations
More Info
More Info
Recombinant Sheep Fibroblast growth factor 2 (FGF2) (Active)
Regular price
$2,310.00
Sale price
$2,310.00
Regular price
Unit price
/per
