1,4-DPCA

Vendor: Abmole

Type: Molecular

SKU: M29928

$103.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
1,4-DPCA, a potent prolyl-4-hydroxylase inhibitor, is a collagen hydroxylation inhibitor in human foreskin fibroblasts with an IC50 of 2.4 µM. 1,4-DPCA inhibits prolyl-4-hydroxylases α isoforms stabilizes HIF-1α protein. 1,4-DPCA also inhibits factor inhibiting HIF (FIH) with an IC50 of 60 μM.
Casnumber
331830-20-7
Formula
C13H8N2O3
Mw
240.21
Psmiles
C1=CC2=C(C3=C(C=C2)C(=O)C(=CN3)C(=O)O)N=C1
Purity
≥98.0%
Solubility
DMSO 12.5 mg/mL (ultrasonic)
1,4-DPCA

1,4-DPCA

$103.50 USD